CONCISE REPORT Impact of tocilizumab therapy on antibody response to influenza vaccine in patients with rheumatoid arthritis
نویسندگان
چکیده
Department of Rheumatology, Clinical Research Center for Rheumatic Disease, NHO Kumamoto Saishunsou National Hospital, Kumamoto, Japan Rheumatic and Collagen Disease Center, Sasebo Chuo Hospital, Nagasaki, Japan Oribe Rheumachika-Naika Clinic, Oita, Japan Institute of Rheumatology, Zenjinkai Shimin-no-Mori Hospital, Miyazaki, Japan Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan
منابع مشابه
Impact of tocilizumab therapy on antibody response to influenza vaccine in patients with rheumatoid arthritis
OBJECTIVES We assessed the influence of tocilizumab (TCZ), a humanised monoclonal anti-interleukin-6 receptor antibody, on antibody response following influenza vaccination in patients with rheumatoid arthritis (RA). METHODS A total of 194 RA patients received inactive trivalent influenza vaccination (A/H1N1, A/H3N2 and B/B1 strains). All patients were classified into the TCZ (n=62), TCZ+meth...
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INTRODUCTION The objective of the study was to investigate the impact of newer biologic treatments including rituximab, abatacept and tocilizumab on antibody response following pneumococcal vaccination using a 7-valent conjugate vaccine in patients with established rheumatoid arthritis (RA). METHODS Patients with RA receiving rituximab, abatacept or tocilizumab as monotherapy or combined with...
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BACKGROUND & OBJECTIVES Patients with autoimmune rheumatic diseases may be at an increased risk of infection due to disease and use of disease-modifying antirheumatic drug (DMARD) therapy. The present study was done to evaluate the immune response to influenza vaccination in patients with rheumatoid arthritis (RA). METHODS Fifty one RA patients on stable methotrexate (MTX) therapy (≥15 mg/wk)...
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